Sentence examples for diverse growth factor from inspiring English sources

These results suggest that SPRED2 is a putative negative regulator in prostate cancer cells and is capable of attenuating MAPK stimulation by diverse growth factor ligands.

Diverse growth factor, mitogen and cytokine engagement of cognate receptors leads to the recruitment of the GDP/GTP exchange factors, growth-factor-receptor bound protein 2 (Grp2) and Sons of Sevenless (SOS) to the plasma membrane where Ras resides.

For example, there are reports of activation of HIF in response to inactivation of a number of different tumour suppressor genes, in response to activation of several different oncogenes and in response to activation of diverse growth factor pathways (see below).

Studies carried out by Becker et al. [16] revealed that local application of diverse growth factors (IGF-I and PDGF) induce the statistical increase in bone repair and the increase of bone density, around Ti implants, compared with the control group.

SPRED2 overexpression blocked ERK phosphorylation and inhibited diverse growth factor-induced proliferation and migration.

27 Other agents are designed to prevent the dependence of malignant cells on diverse growth factors and their receptors.

Multiple studies present evidence that Akt undergoes tyrosine phosphorylation in response to diverse growth factors, such as EGF, Heregulin and insulin.

6, 27 Functional ADAMs are involved in cleavage of diverse growth factors, membrane‐bound cytokines, surface receptors, and adhesion molecules, thus increasing tumor proliferation, migration, and invasion.

In contrast, in most human tumors, MMP-9 expression is basally low but upregulated in response to diverse growth factors and cytokines [ 31– 31].

In regards to cell viability in degenerative IVD, previous studies have investigated the importance of apoptosis and a variety of apoptosis-related signalling molecules, such as cytokines and diverse growth factors, which subsequently lead to the collapse or insufficient rearrangement of a functional ECM equilibrium [ 6, 7].

Rhomboids are serine proteases, conserved across all kingdoms of life, and they regulate processes as diverse as growth factor signaling, mitochondrial morphology, parasitic invasion, and bacterial protein translocation (Freeman, 2008; Urban, 2009).