This was most obvious for large UIR genes, which were upregulated across the diverse experimental test conditions more often than downregulated (upregulated for 57 of 132 conditions versus 42 downregulated).
With this kind of cooking, I typically love the diverse, experimental tastes in the appetizers.
To study this hypothesis further, the prediction network method should be repeated with a dense matrix of assays spanning diverse experimental conditions and compounds tested against all assays.
By attaching a short, well-folded α-helical appendage, a relatively intractable protein can be converted to a protein amenable to testing under diverse experimental conditions, whether in vivo or in vitro.
For external validity, malignancies tested in more and diverse experimental systems tended to show less extreme effect sizes (p < 0.001).
Validation criteria used in this report demonstrated that 18S rRNA presented with the least degree of fluctuation of the six endogenous controls tested with ΔCT ≤ +/−0.5 under four diverse experimental conditions.
In such applications, contributing and diverse experimental data and models need to be combined as evidence supporting integrated testing, safety and risk assessment and regulatory reporting as stipulated under REACH.
Experimental tests 212 9.7.
However, subsequent experimental tests produced mixed results3,4,5,6,7,8,9,10,11,12,13.
