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Abundant data from diverse experimental systems have also implicated Prox1, the vertebrate orthologue of pros [50], in cell cycle exit regulation.
This conclusion is based on the cumulative findings from diverse experimental systems, which included the use of genetic mutants or chemical inhibitors that limit the subcellular localization of ICP0.
Both internal and induced stresses were examined using diverse experimental systems.
For external validity, malignancies tested in more and diverse experimental systems tended to show less extreme effect sizes (p < 0.001).
Using a meta-analytical approach, we studied AP in three diverse experimental systems, which was possible because of the genetic accessibility of yeast as a model system.
Here we summarized data on mitochondrial dysfunction obtained in diverse experimental systems, which are related to conditions seen in intensive care unit (ICU) patients.
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Even within the diverse range of experimental systems, clear themes emerged from the talks.
In conclusion, our study exemplifies the power of using the diverse sets of experimental systems available to study yeast to address a fundamental question, which is to understand the mechanisms underlying maintenance or resolution of AP.
Moreover, research at IMCB reflects diverse scientific interests and experimental systems, ranging from yeast genetics to Drosophila development to mouse genetics.
This includes questions of governance, practical aspects of applying principles to diverse experimental contexts, building enabling systems and infrastructure, incentives and collaborative issues.
This assumption usually holds true when a large number of diverse samples, representing different experimental systems (e.g. different transcription factors in ChIP-chip experiments) and different conditions, are used for model building.
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