Together, our findings define a general principle for how the widespread four-helix bundle cytoplasmic domain architecture can control VGIC responses, uncover a mechanism underlying the diverse BacNaV voltage dependencies, and demonstrate that a discrete domain can encode the temperature-dependent response of a channel.
Human cancer cells display a diverse spectrum of dependencies on PI3K and MAPK signaling pathways, and thereby sensitivity to agents targeting canonical components of these cascades, their upstream regulators, and downstream effectors.
The selection of the photovoltaic system is dependent on diverse factors like cost, efficiency, complexity, technology and array dependency.
We also mapped Ghrh+ cells on E18.5 mice embryos homozygous for Otp deletion, aiming to test the dependency of the diverse Ghrh+ cells groups on an Otp+ background (recapitulating the study of Acampora et al. 1999).
Diversity is, instead, diverse.
Consequently, data stored in separate and diverse tables and documents obviously miss the dependencies to other aspects that might reveal relevant correlations.
✓All cancers, including molecularly defined classes such as HER2+ tumors, are extensively diverse with respect to molecularly aberrations, pathway dependencies, and responses to drug treatment.
This finding is useful as it might possibly improve the diverse energy supply market and decrease the dependency on imported fuels and environmental pollution.
Vietnam is a country with diverse terrain and climatic conditions and a dependency on hydropower for a significant proportion of its power needs and as such, is particularly vulnerable to changes in climate.
The technology of renal dialysis offers a way in which life can be sustained, so it is not surprising that the complex, diverse and evolving iatrogenic aspects of dialysis-dependency continue to be researched.
