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Peroxiredoxins (PRXs) catalyze the decomposition of peroxides and function in diverse compartments to protect cells against damage from reactive oxygen species (ROS) (Dietz 2003).
Up to this point, we had described the different forms of APP, α-secretase, and β-secretase in the diverse compartments, prior to the beginning of APP processing.
In the book, as no doubt in the lectures, he takes his young audience on a tour of the cell's diverse compartments encouraging them to imagine that they are 'cytonauts' exploring the cell's myriad internal structures.
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If you're the kind of person to gather around books, papers and diverse objects you have to find a desk with lots of various compartments to fit all these items.
This newly developed approach can be used to predict free drug concentration in diverse tissue compartments for small molecules in toxicology and pharmacology studies, which can be leveraged to optimize the pharmacokinetics drivers of tissue distribution based upon physicochemical and physiological input parameters in an attempt to optimize free drug level in tissue.
The coupling of CLRs to different signal transduction modules is influenced not only by the receptor, but also by the nature, density and architecture of the ligand, which can affect the rate of receptor internalization and trafficking to diverse intracellular compartments.
Moreover, identified proteins appear to cover a wide variety of biological functions and appear in diverse cellular compartments.
Thus, much like their classical HLA relatives, CD1d molecules survey ligands that originate in diverse intracellular compartments.
This metabolic plasticity allows the bacterium to survive in diverse environmental compartments, such as different soils, water distribution systems [25] and under human skin [26].
Non-canonical roles of tRNA synthetases require their presence in diverse cellular compartments.
Further, targeting to these molecules achieves localization of drugs to diverse endothelial compartments.
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