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These pathways involve the association cortices and the corpus callosum, which connect information in distant brain regions and underlie diverse cognitive functions that support creativity.
We therefore investigated the effects of MT-training on diverse cognitive functions in an exploratory manner.
Considerable evidence demonstrates that cerebellar structures are involved in diverse cognitive functions, including working memory, motor skill learning, explicit memory, and language [ 45].
As described in the Introduction, we investigated the effects of MT training on diverse cognitive functions in an exploratory manner, and we did not necessarily prepare a rationale for the inclusion of all of these measures, although all of the cognitive measures did assess cognitive functions of important domains.
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The mammalian hippocampus, comprised of serially connected subfields, participates in diverse behavioral and cognitive functions.
Thus, our results are congruent with the ideas that creativity is associated with the integration of conceptually distant ideas held in different brain domains and architectures and that creativity is supported by diverse high-level cognitive functions, particularly those of the frontal lobe.
Previous studies have shown impairments on tasks tapping a diverse range of cognitive functions such as memory, planning and executive attention [ 1- 4].
MT plays a key role in human central executive functions, and the PFC regions (DLPFC, IFJ, and LRPFC), ACC, the part of the parietal lobe involved in MT, and the frontoparietal network consisting of these areas are associated with diverse higher-order cognitive functions [Burgess et al., 2005; Derrfuss et al., 2004; Fuster, 2006].
Our findings suggest that participation in MT-training is as a whole associated with task-irrelevant plasticity (i.e., neural changes are not limited to certain specific task conditions) in regions and the network that are assumed to play roles in MT as well as diverse higher-order cognitive functions.
The neuropsychological test battery for the MedLey RCT includes a series of individual cognitive measures to assess a diverse range of particular cognitive functions sensitive to normal age-related effects, and also likely to be affected by dietary factors.
Together, these subtests cover a diverse assessment of particular cognitive functions known to be sensitive to MCI and dementia, with high sensitivity in detecting early AD (sensitivity of 100%) and also in detecting MCI (sensitivity of 80%).
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