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GUARDD will help establish the effective implementation of APOL1 risk-informed management of hypertensive patients at high risk of CKD, and will provide a robust framework for future endeavors to implement genomic medicine in diverse clinical practices.
Furthermore, these studies were published over a period spanning nearly two decades in different regions with diverse clinical practices.
Additional research is needed to account for the utilization patterns over time of these tests and how they influence treatment patterns in diverse clinical practices.
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In addition to summarizing available data on the relative benefits and risks of currently available therapies in diverse clinical practice settings, we reviewed designs of ongoing trials and registries, focusing on areas of methodological controversy and uncertainty.
Effectiveness studies, on the other hand, are arguably more generalizable than efficacy studies because they are larger, take place in diverse settings (e.g., many wound care clinics with varying clinical practices) with diverse patient populations, and are conducted in a real-world setting.
The reasons for these differences may be diverse and include varying clinical practices, different attitudes, cultural backgrounds and, not least, changes in practice developing over time.
[ 4] Active interventions with components ranging from simple reminders given to clinicians, to complex multi-faceted interventions have been tested in diverse settings to improve clinical practices.
We interviewed fifteen physicians with diverse clinical experiences, demographics, and practice affiliations.
Almost a third of the VA Primary Care clinicians, practicing in diverse clinical settings, encountered one or more patients with clinically important treatment delays as a result of missed results during the two weeks prior to administration of our survey.
Copper/copper alloy surfaces have been shown to act as an adjunct to standard infection control practices in diverse clinical settings, continuously reducing contamination by over 90%.
More and more investigators suggest that cancers of different organs of origin, but with the same molecular targets, should be managed together because the common molecular targets observed in diverse tumors determine clinical practice better than organ-based classification [ 31].
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