The health-care system in Zambia is faced with diverse challenges ranging from inequity in the provision of health services to poor quality of care and critical shortage of human resources.
High student-to-teacher ratios are found in most urban schools, and these schools often lack the resources to deal with the diverse challenges they face, including unruly student behavior.
These diverse challenges call for an urgent policy upgrade.
Yet the clinical development of therapies targeting the FGFR signalling pathway presents multiple challenges, with diverse mechanisms of pathway activation combined with multiple inhibitors of differing potency and with antibodies in preclinical development.
Over the last decade, mice with defects in these various nucleotide-sensing TLRs or their downstream adaptor molecules have been shown to exhibit diverse outcomes when challenged with different viral pathogens (Akira et al., 2006; Zhang et al., 2007).
The process of screening to detect early different diseases inherently is fraught with diverse ethical challenges [ 6, 9].
With diverse health challenges, health authorities in Turkey need robust data on the epidemiology and impact of diabetes in order to plan and prioritize their health programs.
While the diverse technical challenges of working with samples such as biominerals make the first possibility likely, the second scenario should also be considered in light of the apparent evolvability of molluscan shell forming secretomes [ 4, 29, 33].
There is a need to undertake research in other contexts with diverse health challenges (e.g. HIV/AIDS), and socio-economic conditions (e.g. worsening economic deprivation), and cultural beliefs and practices.
While highly ranked publications can have a prompt and major personal impact on the involved scientists (e.g. increased funding and advancement of academic career), the actual implementation requires substantially more time and is associated with diverse, unforeseeable challenges, which can bring the process to a standstill.
