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Moreover, Kelch-like ECH-associated protein 1 (KEAP1) has been reported to inhibit NF-κB signaling via the H2O2-mediated degradation of IKKβ.63 These observations imply that ROS in diverse cellular compartments may lead to disparate consequences in redox-regulated NF-κB signaling.
Moreover, identified proteins appear to cover a wide variety of biological functions and appear in diverse cellular compartments.
Non-canonical roles of tRNA synthetases require their presence in diverse cellular compartments.
The ovary is composed of three diverse cellular compartments and tumours can arise from uncontrolled proliferation in each one of them.
Also, the ERK 1/2 and PI3K/Akt/Bad pathways mediate the anti-apoptotic effect of estrogens in C2C12 muscle cells following activation of ERα and ERβ located in diverse cellular compartments such as the mitochondria and perinucleus [ 91].
Stable expression of these intracellular antibodies has been shown to be well tolerated by various cell types, reliably tracing targeted antigens in diverse cellular compartments (Burgess et al., 2012; Helma et al., 2012; Rothbauer et al., 2006; Zolghadr et al., 2012).
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These sensors recognize the diverse range of pathogens in various cellular compartments and lead to the activation of innate immunity, including the production of various cytokines that create an anti-pathogenic environment to limit the pathogen.
A major class of heat shock proteins (Hsps) belong to the ubiquitous Hsp70 family, a diverse collection of 70 kDa chaperones that exist in various cellular compartments.
Acetyl-CoA is generated in various cellular compartments, including the nucleus, the cytoplasm and mitochondria.
Different types of TGs are found in various cellular compartments.
Scaffolds facilitate and direct signalling to various cellular compartments [ 3].
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