Sentence examples for diverse cell lines from inspiring English sources
The importance of this experimental design is that genetically diverse cell lines provide a significant phenotypic diversity for proof of concept and validation.
Using such designer nucleases to induce targeted chromosomal DNA double-strand breaks (DSBs) has greatly expedited genome modification in diverse cell lines and animal models.
It also showed strong cellular inhibition against diverse cell lines including HCT-116, MCF-7, MDB-MB-435 and NCI-460, with GI50 values of 0.35, 0.22, 0.51 and 0.48 μM, respectively.
Other studies have demonstrated the benefits of HAM as a substrate for ex vivo expansion of diverse cell lines such as limbal epithelial, corneal and conjunctival epithelial cells (Grueterich et al. 2002; Pellegrini et al. 1997).
These results show the potential for USEP to kill cells preferentially based on inherent susceptibilities across diverse cell lines.
Thus, levels of enrichment of EZH2 and H3K27me3 correlate very well (inversely) with the levels of CDKN1C expression across these diverse cell lines.
Here we outline several laboratory-based models that can be used to assay the influence of genetic variability on an individual's response to chemicals: 1) genetically-diverse cell lines, 2) human primary cells, 3) and genetically-diverse mouse panels.
We have simultaneously evaluated 185 candidate pancreatic cancer genes, selected as those recurrently and focally amplified or deleted, by a pooled shRNA library screen on 10 genetically-diverse cell lines.
Proliferation and differentiation of the diverse cells lining the respiratory tract are influenced by complex signaling and transcriptional programs that are active during formation of the respiratory epithelium and during its repair.
As a result of private research, more than 60 genetically diverse stem cell lines already exist.
