Exact(4)
In tobacco plants the effect of antisense down-regulation of various genes encoding enzymes of the monolignol biosynthetic pathway resulted in quantitative and qualitative changes in lignin distribution and in diverse alterations of the secondary wall assembly of modified tobacco plants.
Because OPN in known to exhibit diverse alterations in isoform expression that are related to its biological activity, we evaluated potential OPN protein isoform expression changes induced by our short-term HFD protocol using SDS-PAGE/western blotting.
Profiling of an A. thaliana line with a homozygous T-DNA insertion into the coding region of AtMTP6 shows consistent diverse alterations in the ionome with reduced levels of Mg, Mo, and Ca and increased levels of Na, K, Mn, and Cd.
Application of the data analysis pipeline outlined in Figure 1 revealed that the most thematically diverse alterations specific for C57BL/6.NOD- Aec1Aec2 mice, involving the most EM-related GSs and EM-associated GSs, occurred between 4 and 8 weeks of age.
Similar(56)
Further research in LV proteome showed that moderate treadmill running led to diverse alteration in the contractile, stress-related, and metabolic function of cardiac proteins, where heart fatty acid binding proteins (HFABP), thioesterase-1, and short-chain acyl-CoA dehydrogenase were upregulated [ 98].
Hepatocarcinogenesis is considered a slow process in which diverse genomic alterations accumulate, altering the phenotype of hepatocytes and hence leading to multiple monoclonal and dysplastic hepatocyte populations (Thorgeirsson and Grisham, 2002).
To differentiate these diverse functional alterations and identify age-associated transcriptome alterations that are specifically related to genome stability, we here performed a more detailed analysis on gene sets associated with telomere maintenance and -repair, chromosome segregation and -maintenance as well as DNA double-strand repair (See Supplementary Table I).
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse genomic alterations underlying human cancers.
Studies have demonstrated diverse genetic alterations in osteosarcoma cells including structural abnormalities, gain and/or loss of chromosomes, mutations in tumor suppressor genes and epigenetic modifications (Kansara and Thomas, 2007; Broadhead et al., 2011).
Such diverse glomerular alterations are less common in acute anti-GBM disease [ 16].
However, the prognostic implication of diverse molecular alterations along bowel subsites is not well understood.
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