Even if multicopy hairpin precursors could yield the same mature miRNA sequences, another product, termed as miRNA* species, always diverged, such as hsa-let-7a-1* and hsa-let-7a-2*, hsa-let-7f-1* and hsa-let-7f-2* (Figure 3A).
We also noticed that genes related to 'Xenobiotics metabolism' were highly diverged, such as carboxylesterase clade E (95.13%), two GSTs (95.19%, 96.26%) and two UGTs (95.45%, 95.56%) (Additional file 6).
Kim et al. also found that PI transcripts were detected in petals, stamens and carpels in early-diverging such as in Amborella trichopoda and Nuphar advena (Kim et al. 2005).
Thus, it represents a key lineage that can provide insight when compared to other later diverging fungi such as the ascomycetes and basidiomycetes.
This group may include novel lizard genes and rapidly diverging genes such as noncoding RNAs.
Most early diverging plants, such as P. patens, are haploid-dominant during most of their life cycle, while angiosperm plants have undergone rounds of WGD [ 21- 23].
Genomic data from additional "early diverging" angiosperms, such as Nymphaea and Amborella, will provide more detailed insights into mitochondrial genome evolution in early angiosperms.
The relationships among cytosolic epimerases of eukaryotes are poorly resolved, with only recently diverging groups such as vascular plants and metazoa recovered with strong bootstrap support.
In addition to the partitioning of ancestral functions, we might also expect to detect apparent neofunctionalizations of gene duplicates, particularly when we compare deeply diverging lineages such as vertebrates and urochordates.
RNA editing data from an angiosperm from an "early diverging" lineage, such as Amborella or Nymphaea, would help polarize the degree of editing loss in Liriodendron, which looks to be exceptionally low based on these data.
In comparative studies, it is often useful to compare across wide phylogenetic spans and, within angiosperms, to include representatives from basally diverging lineages such as the genomes reported here: Nuphar advena (from a basal-most lineage) and Ranunculus macranthus (a basal eudicot).
