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In contrast, 2008 isolates were antigenically divergent when compared to 2007 viruses; indicating highly antigenic divergence between viruses isolated at close time points (Table 2).
Recently, a comparative genomic analysis by using DNA microarrays demonstrated that these CJIEs were present in C. jejuni strains from various geographical locations and from both clinical and veterinary sources [40], and the coding sequences within the CJIEs from these C. jejuni strains were highly divergent when compared to strain RM1221 [40], [44].
The genotypes of T. gondii strains isolated from Brazil were highly divergent when compared to the previously described clonal lineages.
This pattern is typical of the poorly known P superfamily of conotoxins, whose sequences are however quite divergent when compared to turripeptides [ 108].
The general trend in Table 2 suggested that sense transcription is less divergent when compared to antisense in the three culture conditions when we consider both " the same species and in different conditions" and " different species and in same conditions".
However our sequence and phylogenetic analysis revealed that this protein was divergent when compared to other apicomplexan orthologues and that the critical residues were not conserved (Fig. 1A and B).
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By comparison, several branches and clades did show evidence of accelerated evolution or divergent selection when compared to other groups.
In contrast, AcPbx lacks any PBC-A domain and has a strongly divergent HD when compared to other Pbx proteins.
However, PTSD shows divergent findings when compared to the other anxiety disorders in the rostral anterior cingulate and ventral and dorsal medial prefrontal regions [ 91].
OdH3ts, however, are more divergent than mammalian H3ts when compared to canonical H3.1/H3.2.
Thus, it seems likely that gene-specific transcriptional mechanisms will be divergent in these parasites when compared to other well studied eukaryotic models and this view is supported by recent searches for general transcription factors in these parasites [ 46].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com