In just two days of trial, divergent strategies at best, and strains at worst, among the defense lawyers are already becoming clear.
However, there might be specific treatment effects in the network that lead to inconsistency, e.g. due to being based on studies with divergent patient or trial characteristics [ 5, 6] or due to bias [ 7].
Bijl et al reviewed trials of disease management programs that included screening, they commented on the 'highly divergent' methodological quality of trials yet did not report a formal assessment of trial quality.
21 The channelling bias, that is, that more severe patients (for COPD or other comorbidities) received a prescription of Respimat rather than Handihaler, was considered to explain such divergent results from the trial.
This could be a possible explanation for the divergent results in the present trial and the previous 2002 trial; in 2002 no children had received VAS at birth.
Therefore, assessment of the variability of blood glucose levels might be necessary to fully understand the divergent results of these trials.
One possible explanation for the divergent results among such trials may relate to the incidence of severe hypoglycemia sustained by patients in the interventional arms of randomized trials [ 6- 11].
Recently, several studies have used different study designs, which may provide insight on the effectiveness of eicosapentaenoic in cancer cachexia and also on potential sources of divergent results in previous trials.
This result may not be representative of other, more closely related species in the cluster because D. seriema and D. buzzatii were so reproductively divergent (in mate choice trials, Oliveira et. al., unpubl. data) that alterations in CHCs had little effect despite the significant CHC differences between them.
The RMS error curves in Figure 6 were computed from the estimation errors recorded in each of the 100 Monte Carlo trials, excluding the divergent realizations.
