In addition to the genetic differences between the Wistar, DA and SD rats, ENU mutagenesis can be another reason for the divergent tumor spectra observed between our Tp53 knockout rat and the TP53-deficient Wistar rat (van Boxtel et al., 2011).
To generate dual-reporter plants expressing luciferase isoforms that emit light with divergent emission spectra, we used ProACT2 PpyRE8o as the root structural marker and ProZAT12 LUC (Miller et al., 2009) and ProDR5 LUC+ (Moreno-Risueno et al., 2010) lines that were transformed with the ProACT2 PpyRE8o construct.
Both would, it's fair to say, be worthy and welcome winners, though they are at somewhat divergent ends of that spectrum.
These genes encode a broad spectrum of divergent proteins associated with notochord formation and function.
These findings demonstrate an apparent overlap in specific white matter architecture underlying the normal variance of divergent thinking, openness, and psychotic-spectrum traits, consistent with the idea of a continuum.
Based on their proven broad spectrum of activity against divergent HIV strains in the clinic, both these drugs make excellent candidates for PrEP.
However, ECM interaction and focal adhesion pathways lead to divergent intercellular interaction and a broad spectrum of downstream responses, making it difficult to trace specific molecular interaction cascades and downstream activation targets.
Palaeoclimate reconstruction on the northern Tibetan Plateau resulted in a large spectrum of different and partly divergent interpretations for the climate evolution during the late glacial and the Holocene.
Thus, one potential explanation for the divergent results could be that the pathological spectrum of the cases, in particular regarding B cell infiltrates, differed between the studies.
