Exact(7)
A set of 100 reference sequences was compiled by combining 65 representative group M sequences curated by the Los Alamos Sequence Database and an additional 35 samples added so that the dataset would include three or more divergent reference sequences for each pure subtype and many of the most common CRFs.
These regions were selected to test the robustness of probes designed from a divergent reference.
Alternatively, in many cases it is necessary to apply more divergent reference genomes from extant genus- or family-level congeners when sequencing extinct taxa [ 12, 22].
Our aim was also to map the more divergent reads to obtain a higher coverage of the polymorphic community on the divergent reference.
Nonetheless, even in whole genome sequence data, alignment to a divergent reference genome [ 64] or removing sites with a high proportion of missing data across taxa can generate ascertainment bias in the analyzed data set [ 65].
(3) It has a strong capability to identify variants based on a relatively divergent reference genome, which brings it to a much wider application other than re-sequencing projects.
Similar(53)
Later, Gold reviewed the restaurant, in the style that has come to be his signature, a postmodern scrapbook of divergent references that run with the internal logic of a dream.
High uncertainty, high information asymmetries between actors, high transaction costs, high grade of probable spillovers (low level of appropriation), and different (divergent) time reference interests are all recurrent obstacles.
Gene coverage and expression analysis was further investigated in the non-model context by using increasingly divergent genomic reference species to group assembled contigs by unique genes.
We tested how accurately these known RM11-1a SNPs were rediscovered using the Illumina 1 G reads aligned with the divergent S288C reference sequence.
We also found that the percentage of mapped reads in S1 (32%) is slightly higher than that in S2 (27%), indicating that pooled plasmids in S2 may be more divergent from the reference plasmids than those in S1.
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