In addition to correctly predicting the divergent pattern of cell sizes, this model reveals allometric growth of cells within the network, an emergent property of this system and a feature commonly associated with differential growth on an organismal scale.
In addition, these findings illustrate the critical importance of evaluating T cell function and fate within the tumor site during the development of immunotherapeutic protocols, as highly divergent patterns of T cell phenotype, function, and fate were present in the tumor relative to peripheral lymphoid organs.
Our findings indicate that when Notch activity is present at mitosis, the two daughter cells maintain similar Notch activity levels, while absence of Notch activity during mitosis correlates with divergent patterns of Notch signalling in sibling cells that may indicate the adoption of different cell fates.
We also identified divergent patterns of colostrum Env-specific B-cell lineage evolution with respect to crossreactivity to gastrointestinal commensal bacteria, indicating that commensal bacterial antigens play a role in shaping the local breast milk immunoglobulin G (IgG) repertoire.
The divergent patterns of drug sensitivity of human cancer cells across HDAC inhibitors we observed allowed us to conclude that each inhibitor, including those that have selectivity for class 1 HDACs, must have activities beyond just HDAC inhibition, which contribute to overall drug effects such as cytotoxicity.
First, transcripts showing similar or divergent patterns of differential expression between the EGF- and HPX-stimulated MDA-MB-468 cells were extracted (Additional file 3: Figure S2a & b, respectively).
Altogether, our findings provide empirical evidence for divergent patterns of storage and turnover of SON between arid and semiarid grasslands.
Moisse, K. et al. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury.
"These differences were probably critical" to the divergent patterns of diabetes between those in the Mediterranean diet groups and those in the low-fat diet group, they wrote.
The others show divergent patterns of gene expression.
