Exact(4)
These divergent functional categories will be discussed in further detail.
Other divergent functional categories include: sulfur/nitrogen metabolism (34%), transcriptional regulators/σ-factors (47%), signal transduction (49%), cell envelope (37%), chemotaxis (70%) and antibiotic resistance (36%) (Table 3).
These genes belong to divergent functional categories or pathways.
Analyses of sequences across human, chimpanzee and mouse genomes indicate that one of the most divergent functional categories includes the genes involved in reproduction [ 32].
Similar(56)
Nevertheless, a number of other major functional categories are more divergent.
This trend was mainly due to the highly divergent Platypus, where the number of biased functional categories rose from 21 to 27 when error was removed.
Functional categories show significant N S ecological putative adaptive divergent upregulation of genes highlighting a higher metabolism in N and kidney urine cycle pathways in S.
It is consistent with the previous reports that approximately 50% of examined transcripts are accumulated at a detectable level and encode all functional categories of proteins in dry seeds of divergent plant species [ 27, 28, 33].
This table contains the top 15 enriched transcription factors binding sites found in the promoters of divergent genes, with literature references that link these factors to general functional categories of tumor progression, cell cycle, and development.
These genes belong to functional categories known to confer adaptive advantages, and their highly divergent evolution could be a consequence of local adaptation to the African or Asian environments, or of human selection following the independent domestication processes.
Here, by cross-species analysis of a large set of functional categories and all transcription factors and growth factors, we reveal conserved and divergent functional landscapes underlining fundamental and species-specific mechanisms that regulate ESC development.
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