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These results further reveal a divergent effect of the particulate versus organic components of diesel exhaust, in that DEPEs induce CYP1A1, whereas the particulate reduces CYP2B1 and phase II metabolic enzymes.
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Research in rodents and humans has shown divergent effects of the glucocorticoids corticosterone and cortisol (CRT) on reward processing.
Interestingly, t10,c12-CLA had no effect on foam cell formation, consistent with the divergent effects of the two CLA isomers in atherosclerosis (Arbonés-Mainar et al, 2006).
Actual expression of the mutated allele was checked by RT-PCR and sequencing of the cloned transcripts and is also reflected by the divergent effects of the presence of this allele on different carbon sources.
By subdividing the context of the emotional maltreatment to relational and peer victimization, it was possible to identify the cumulative and divergent effects of the type and context of maltreatment.
Table 5 examines the ability of sex hormone changes from baseline to year 1 following randomization to mediate the divergent effects of the two hormone therapy regimens on breast cancer incidence.
It is a well-known phenomenon that stimulation of a receptor in increasing dosages may show a bell-shaped response [ 20, 21], explaining divergent effects of the same dosage depending on the receptor affinity and/or amount at different sites of the GI tract.
The mechanisms leading to the divergent effects of these chaperon proteins regarding Pim1 are not understood.
Here we separately block monocyte recruitment by the use of CCR2−/− mice and specifically deplete neutrophils by an antibody specific for these cells and are therefore able to distinguish the divergent effects of these two cell subsets.
Consistent with the variability of MSCSYT-SSX1 transcriptome relatedness to SS signatures and that of GO term overrepresentation, single population analysis limited to datasets of epigenetically regulated genes showed marked qualitative and quantitative differences among the four hMSC isolates, the most striking being the divergent effect of SYT-SSX on the expression of imprinted genes.
The explanation for the observed divergent effect of PPARγ phosphorylation at the relevant serine is lacking.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com