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We therefore evaluated M2-based vaccine efficacy against divergent challenge viruses.
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But loose monetary policy in the rich world makes it hard for emerging economies to tighten even if they want to, since that would suck in even more speculative foreign capital.Walking a fine lineWhether the world economy moves smoothly from the Great Stabilisation to a sustainable recovery depends on how well these divergent challenges are met.
Multiple divergent lineages challenge the design of cross-protective vaccines and highlight the need for additional surveillance.
However, it does rather skirt over some of the other reasons Europe is in such a mess today – eg, a single currency union covering such divergent countries, the challenge of implementing austerity without devaluation, the lack of political leadership in the early stages of the crisis.... maybe they're in another video?.... Best watched alongside Ian Traynor's analysis of Project Europe, I reckon.
Haldane concedes that this divergent picture poses challenges for monetary policy, with some parts of the economy "going gangbusters" while there is "continuing pain" for others.
The circulation of multiple divergent hemagglutinin lineages challenges the design of effective cross-protective vaccines and highlights the need for additional surveillance.
Eliciting maximal immune responses to highly divergent viruses is a challenge and a focus in AIDS vaccine development.
Hence accurate identification and de novo assembly and annotation still remains a challenge for divergent sequences among emerging pathogenic species.
Furthermore, recombinant modified vaccinia virus Ankara (MVA) vector expressing HA from H5N1 A/Indonesia/669/06 andndonesiA/Anhui/01/05 A/Anhui/01/05 viruses (MVAtor-tri-HA vector) elicited potent cross-neutralizing protection in mice against H5N1 challenge from divergent clade.
Even so, one generation of divergent selection based on challenge test data has been shown to result in significantly higher average rates of survival (73.3 ± 3.3% versus 16.7 ± 3.3%), blood phagocyte respiratory burst activity, serum myeloperoxidase activity and ceruloplasmin level in resistant compared to susceptible line rohu [ 5].
Deciphering whether a pair of duplicated genes has evolved divergent functions is often challenging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com