Sentence examples for divergent cell lines from inspiring English sources

The discrepancy in previous studies may be caused by the divergent cell lines, methodologies, and conditions used by different groups.

We find that these divergent cell lines communicate reciprocally and cooperate to invade collectively dependent on protease activity and fibronectin deposition and without altering MITF expression.

Herein, we investigated the viability of microcapsules in various tissue-derived mesenchymal stem cells, including rat bone marrow mesenchymal stem cells (BMSCs), adipose-derived stem cells (ADSCs), synovium-derived mesenchymal stem cells (SMSCs), and divergent mouse cell lines (mouse fibroblast cell line C3H10T1/2, mouse myoblast cell line C2C12, and mouse preosteoblast cell line NIH/3T3).

Finally, to substantiate the role of Mss4/eIF3f interaction in protection of stress-induced apoptosis, we transiently transfected divergent A7 melanoma cell lines that constitutively expressed different levels of either endogenous, recombinant wt or F75A mutated Mss4 proteins with a plasmid coding for human eIF3f and subsequently subjected them to hydrogen peroxide stress for 8 h.

The present studies demonstrate for the first time that KLK6 is able to promote survival of murine splenocytes as well as the human leukemic Jurkat T cell line across divergent cell death paradigms encompassing both the intrinsic/mitochondrial and the extrinsic Fas-Fas ligand-induced apoptotic signaling pathways.

In this manuscript, we present the divergent responses of these cell lines to hypoxia and to DNA-damaging agents.

This study is the first to characterise the post irradiation transcriptome of two prostate cancer cell lines with divergent responses to RT commonly used in research.

The identification of species-specific DREs is consistent with the divergent regulation of GSTA5 between these cell lines.

Another interesting finding in this study is that NSAIDs can exhibit divergent effects on OA in CML cell lines.

Given the highly divergent nature of the AR-positive cell lines 22Rv1 and LNCaP we repeated the proliferation experiments using the androgen sensitive LNCaP and LNCaP-SSR, an AR-positive castration resistant LNCaP-subline.

Whilst we acknowledge that cell lines may be divergent from their ancestral tumour and not wholly representative of the full diversity of ovarian cancer, we believe our classification represents a foundation for further development, particularly since ovarian cell lines can be assigned to unique ovarian tumour subtypes and are not derived from any random scheme.