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Then, the two, four, six and eight more divergent categories were subsequently removed from the two alignments described above.
In castor bean, the same number of 23 cis-NAT pairs appeared in the enclosed and divergent categories and 17 were convergent (Additional file 2: Table S10).
At the other end of the scale, immune responses and adhesion processes are shared divergent categories and reproductive processes are relatively divergent in both vertebrates and arthropods, whereas divergence of DNA metabolism is common to arthropods and fungi.
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GACK algorithm does not give information on the degree of divergence of individual genes in the divergent category [45].
In contrast, SNPs within GO: 0001640 category (the most divergent category) showed positive correlation between evolutionary rate and recombination rate, although the correlation was not statistically significant as it referred to only one gene (fig. 1 C, r = 0.102, P = 0.325).
Finally it can be used to generate subgroup profiles, in which the various functionally-divergent categories of residues are annotated automatically.
Because the sampler classifies the input sequences at the same time, it can be used to generate subgroup profiles, in which functionally-divergent categories of residues are annotated automatically.
Based on these assignments, the sampler optimally assigns the input sequences to the N subgroups (the rows) and, at the same time, finds M patterns that optimally differentiate the foreground from the background (based on the hyperpartition specification) for each of the M functionally-divergent categories (the columns).
The relationships between distinct sequence subgroups within a protein class are specified using a hyperpartition, which consists of a N × M matrix that assigns N sequence subgroups to the foreground, background or non-participating-sequence partitions for each of the M functionally-divergent categories to be modeled.
This is rather unexpected, since if anything one would have anticipated, that there would have been biological differences between such divergent clinical categories of the disease.
These divergent functional categories will be discussed in further detail.
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