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The data suggest that there are divergent and complex effects of PIP2 on TRPC channels.
They demonstrate that allele specific expression patterns within genes and across tissues can be extremely divergent and complex, when looking at multiple SNP in many tissues.
Based on the similar coenzyme-binding structure, their active-site relationship and repetitive patterns, five SDR superfamily types have been discerned from different data banks, named as "classical", "extended", "intermediate", "divergent" and "complex" SDR enzymes [ 12].
Key to the divergent and complex roles of MMPs and TIMPs on cell proliferation is the discovery that metalloproteinases affect the bioavailability of numerous growth factors and cytokines (Table 1 >).
Despite phage divergent and complex evolution, the thorough molecular analysis of a few paradigmatic tailed phages belonging to different morphological classes, such as Siphoviridae SPP1 and λ, Myoviridae T4 and Podoviridae P22 and Φ29, suggested that only a limited number of structural solutions are used in order to produce a functional virion [ 16– 16].
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Strikingly, over one third of all families as conventionally defined contain representatives from the highly divergent "robust" and "complex" clades.
AMA4 RON2L1 pair is the most divergent AMA RON complex and is predominantly expressed at the sporozoite stage according to ToxoDB.
Five of these (Oculinidae, Euphylliidae, Meandrinidae, Siderastreidae, Astrocoeniidae) have members placed in both of the highly divergent "complex" and "robust" subgroups [2] [5].
Conserved domains of RanBPM protein are responsible for interactions and complex formations with a physiologically divergent group of proteins.
Both Mendelian disease genes and complex disease genes indeed tend to have more divergent homologs than non-disease genes.
Both complex 1 and complex 3 were enriched in the category "cell wall", but with genes indicating divergent functions in the two complexes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com