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Finally, divergent ancestry was checked using EIGENSTRAT [ 20] to detect possible population stratification.
In population genetics, an important application of multi-ethnic studies is the mapping of ancestry in modern populations consisting of an admixture of populations with geographically divergent ancestry.
Control data (Hapmap release #3) were employed through a principal component analysis to exclude individuals with divergent ancestry, and samples with gross chromosome rearrangements or discordant sex information were removed.
Alternating regions of low and high SNP diversity are apparent in which low variation intervals represent strains sharing identity by descent, compared to high variation intervals that represent divergent ancestry.
All participants had a 'white British' background (a principal component analysis was carried out, and samples were excluded based on divergent ancestry, see section on the genotype arrays below).
Principal component analysis (PCA) to test for individuals with divergent ancestry compared with CEU HapMap3 samples was performed as detailed previously (49), and as a result four further individuals were excluded (Supplementary Material, Fig. S7).
Similar(53)
On the contrary, we infer that most differences between haplotypes at mutation selection equilibrium in the microsatellite case reflect the deeply divergent ancestries of the haplotypes.
Specifically, are these similar pathogens the products of divergent (recent common ancestry) or convergent (common pathogenic traits incorporated into different genetic backgrounds) evolutionary processes?
Considering that S. flexneri strains of serotypes 1 5 share a recent common ancestry, the divergent oac1b is more likely to have been obtained from outside S. flexneri than to have undergone rapid divergence from the oac gene in the other serotypes (3a, 3b and 4b) within S. flexneri.
People in Amazonia have ancestry from two divergent sources...we think this is a real observation".
The topology might suggest that MY-KN may have had an ancestry that is more divergent than those of the other Malay populations.
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