Sentence examples for divergent alterations from inspiring English sources

Future studies are needed to unravel the mechanism behind the divergent alterations in IFN response gene activity upon TNF blockade.

Overall, we found divergent alterations for mRNA and protein content of COX-2 in tumor tissue, which confirms our results in previous investigations [ 12].

Thus, we focussed our analysis towards elucidating the convergent and divergent alterations to intracellular signalling which may encompass therapeutic targets for controlling EMT within MDA-MB-468 cells as a model of triple-negative breast cancer (TNBC).

To assess whether the observed divergent alterations in OA translate into changes in tyrosine kinase inhibition, the IC50imatinib was examined in K562 and KU812 cells with or without diclofenac or ibuprofen.

In order to address this question, we performed a four-way interrogation of gene expression profiles: 1) normal urothelium versus SCCa, 2) normal urothelium versus UCa, 3) normal urothelium versus SCCa and UCa combined (shared alterations) and 4) UCa versus SCCa (divergent alterations).

Herein, the cytological development and histochemical profile of Nothotrioza cattleiani galls, a sucking insect, on the leaves of Psidium cattleianum are compared with those of other galls, especially N. myrtoidis galls, searching for conserved and divergent alterations in cell fates and cycles.

Similarly, repeats are highly divergent between KNL1 orthologs, displaying alterations to the canonical MELT motif as well as the presence of additionally conserved motifs, for example, TΩ, SHT and other potential phosphosites ([EDN]x[ST] or Rx[ST]) (e.g., insects in fig. 2).

One of the key findings from the genetically engineered mice is that distinct genetic alterations clearly underlie phenotypically divergent urothelial tumors.

Such potent and divergent responses to naturally occurring subtances suggest that alterations in their homeostatic regulation could have etiological significance in mental illness.

The 159 genes revealed as having strongly divergent expression patterns as a result of copy number alterations identified a remarkable pattern of gene deregulation in several key biological pathways.

This is particularly evident when two divergent epigenomes come together in a hybrid resulting in thousands of alterations to the methylome.