Exact(2)
To verify that overall repeat element divergence patterns can be estimated accurately from low-coverage genomic shotgun data, we subsampled the human genome to produce five datasets comparable to our copepod data and estimated pairwise divergence of repeats as described.
Analysis of the sequence of repeats revealed that a major driving force for divergence of repeats is insertion and deletion of sequences between the N-terminal CXXC motif and the IZF and between the IZF and the three CXXC motifs.
Similar(58)
Sequence divergence of repeat elements indicates recent/ongoing repeat proliferation.
As a measure of sequence divergence of repeat family α in region γ, we then computed the LogDet time distance (Barry and Hartigan 1987), (2) One should remark that the substitution rate matrix qγ is scaled such that its trace is independent of γ and always equal to −4 to ensure consistency between equations (1) and (2) (Karro et al. 2008).
To summarize global historical patterns of repeat proliferation and deletion in M. edax, we estimated divergences of repeats from their ancestral sequences (i.e. pairwise divergences) in the somatic and germline genomes.
To summarize global historical patterns of repeat proliferation and deletion in M. edax, we estimated divergences of repeats from their ancestral sequences (i.e. ancestor descendant pairwise divergences) in the somatic and germline genomes.
Sequence divergences of repeat elements in both genomes show a skew towards younger elements, indicating recent/ongoing repeat proliferation.
Pairwise divergences of repeat elements in both genomes are skewed towards younger (i.e. less divergent) elements, with the highest proportion of repeats showing <1%% divergence from the consensus.
Specifically, the mean divergence of cod repeats was 0.268 base substitutions/site, whereas the mean distance among repeats of the other teleosts ranged from 0.676 base substitutions/site for tilapia to 0.839 for zebrafish, suggesting that the cod repeats diverged much more recently than those of other teleosts.
As stated above, the other HNWD genes are likely additional incompatibility genes whose interacting partners are unknown, so that incompatible interactions with het-c may not be the only interactions that promote divergence of the repeats.
We argue that this is not surprising given the remarkable divergence of such repeats.
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