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Ten strains were found to have unusually high levels of divergence compared to the rest of the genus.
Quite surprisingly it was recently found that the murine orthologs of ZIPk underwent a unique type of sequence divergence compared to other vertebrate species.
The most surprising result is the basal position of PAP Morph 5 and its high level of genetic divergence compared to other sympatric P. apicalis.
Sequences of 10 out of 12 strains for subtype D clustered together, and with a reference sequence from Uganda indicating a strong phylogenetic relationship and lesser genetic divergence compared to subtype A sequences.
In several insect species, the Ndc80/Nuf2p sequences returned from the tBLASTn search of the whole genome shotgun sequences showed either exceptionally high or low sequence divergence compared to D. melanogaster.
Conserved antisense transcribed regions also have lower sequence divergence compared to the unconserved regions.
Similar(32)
Such suboptimal alignments appeared abnormal because they had extreme fluctuations in genomic divergences compared to their flanking sequences and were always associated with multiple gaps.
The latter three populations exhibit relatively high genetic divergences compared to the rest of the Eurycea neotenes complex [average uncorrected p-distances 1.2% (White Springs) and 0.7% (Bullis Springs 9 29 & 9 83)].
Such horizontal transfer is supported by the incongruence of the gypsy and species phylogenies and by the low levels of gypsy divergence when compared to the divergence of host genes from the same species.
The level of divergence was compared to the distribution of divergence levels built using a pseudo-random sample of 1,000,000 amino acid site columns sampled with replacement from the alignment (one site could be sampled more than once).
This difference could be indicative of a different host-immunologic response within this tissue resulting in the persistence of infected cells for longer periods – if archival sequences are able to persist in this environment they would drag the average divergence down compared to more divergent, contemporaneously circulating virus in the PL [22].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com