Sentence examples for divergence changes from inspiring English sources

Thus, to ensure more accurate analyses, we did not use the correlation between structural divergence and Ks to investigate how structural divergence changes over time.

However a post-hoc analysis of the proteins in which sequence divergence changes the prediction yielded some proteins with atypical (i.e. not MPP-cleaved) matrix targeting signals as well as a few misannotations.

In a conventional MK, a Fisher exact test is used to identify genes under selection by identifying genes that depart from the expectation that P s / D s ≈ P N / D N, where PS and PN correspond to the counts of synonymous and nonsynonymous (replacement) polymorphic changes, and DS and DN correspond to the counts of the synonymous and nonsynonymous divergence changes.

Then, we used the programs FunDi and GroupSim to validate the hypothesis that the conserved domains were associated with divergence (change) in function among GAs, and performed the GroupSim to identify the specificity determining positions (SDPs) [ 60– 60].

Type I functional divergence detects changes in evolutionary rates between clusters indicative of changes in constraint or selective pressure, while both the SDP algorithm and Type II functional divergence aim to identify residues that are conserved within a cluster but show a change in amino acid properties between clusters.

It is often possible to attribute an apparent change in the rate of substitution to some other factor, such as misspecification of the substitution model, inaccurate divergence dates, changes in base composition, or a transient and locus-specific burst of adaptive changes.

Positive selection is detected as an excess of nonsynonymous/synonymous divergence (fixed changes between species) compared to nonsynonymous/synonymous polymorphism (in our case human Cernunnos-XLF polymorphism).

By examining the trophic anatomy of a lineage using both morphometric and biomechanical analyses, we can improve our understanding of how the diversification of head morphology is linked to ecological divergence via changes in feeding performance [ 3].

The classical MK test (McDonald and Kreitman 1991) posits that, under neutral selection, the ratios of nonsynonymous-to-synonymous nucleotide substitutions should be the same for divergence (fixed changes) and diversity (polymorphisms).

In addition to the importance of topological domain and insulator conservation described here, the evolutionary dynamics that couple intra-domain CTCF divergence with changes in the local domain structure emerge as potentially fundamental for genome regulation.

Exchange of genetic information through gene conversion or ectopic recombination between tandem gene copies following duplication can also obscure divergence because changes in one of the duplicated gene copies may be erased.