Exact(1)
However, shared chromosomal polymorphisms between the M and S molecular forms of An. gambiae and insufficient information about their relationship with ecological divergence challenge this view.
Similar(59)
The large range of operation, the huge number of particles and the need to focus the divergence, present challenges in the design and construction of such a device.
The large range of operation, the huge number of particles and the need to focus the divergence present unprecedented challenges in the design and construction of such a device.
While this divergence presents some challenges, the lack of conservation could be exploited in species-specific targeted therapeutics.
This "progressive divergence model" was challenged by Seidel, Sander, and Elinson [ 3- 5], who noted that earlier stages of development (such as patterns of cleavage) have relatively divergent morphological patterns among species, and so do not always fit the rule.
But although changes in isolated genes underlying differences between ecologically divergent sister species have been linked to changes in the environment (Cobbett and Goldsbrough 2002), evolutionary pressures acting on the genome as a whole and the specific role of environmental pressures on divergence have been challenging to study.
In such instances, divergence time estimation is challenging and the analysis becomes sensitive to the rate model used.
Although our study has provided some insight into the genomic architecture of M S divergence, two additional formidable challenges remain for understanding ecological adaptation and speciation in A. gambiae.
Another challenge is the divergence of interests between central and local governments, which has consequences for the implementation of policies and the operation of child care centers.
Incorporation of gene conversion data into the equations for calculating interspecies divergence may be still a challenge requiring detailed knowledge of a particular genomic region.
These data demonstrate a remarkable burst of organelle genome evolution in dinoflagellates following divergence from Apicomplexa, and also challenge our understanding of the mechanistic details of genome maintenance and expression, most notably translation termination.
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