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The divergence achieved was high, i.e. 3 genetic standard deviations [ 22], and was confirmed over successive cohorts raised in the same flock between 2005 and 2009 (RR, unpublished data).
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Beyond 1% divergence is achieved, but the divergence meter gives a strange output and none of Okabe's friends have any memories of him.
This result is in contrast to a divergence hitchhiking model of speciation with gene flow whereby genome-wide divergence is achieved by expansion in the physical size of initial islands of divergence.
In this study, the value of divergence coefficient achieved is significantly larger than zero, indicating good functional divergence signal between the clusters.
After hacking into SERN's database with the IBN computer, 1% divergence is achieved.
Divergence is achieved via regional restricted methylation of DNA as well as numerous post-translational modifications of the histone proteins (PTMs).
The limit of divergence is achieved if the sex-specific sex chromosome is lost altogether, as occurred in the Ryukyu spiny rat (Kuroiwa et al. 2010).
A driver of these fitness phenotypes is differential allosteric enzyme regulation, indicating isozyme divergence to achieve more-optimal control of metabolism.
However, divergence in many systems can reach points whereby some level of divergence has been achieved but is balanced by other factors that prevent it from moving further [ 5- 8].
Ken Weiss emphasized this in a discussion of the importance of niche construction and behavior-driven evolution when he concluded that "local divergence can be achieved by behavioral sorting by which organisms find or modify local niches according to their abilities, but this need not involve fitness differences nor even be based on genetic inheritance" (Weiss 2004, p. 203).
This functional divergence is partly achieved by differential flexibility of a loop that is rigid in RIG-I, but disordered in MDA5, resulting in different RNA binding preferences.
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