The 3243A>G mtDNA mutation disturbs the function of tRNA leucine 1 (UUA/G) and impairs the ability of mitochondria to make proteins, use oxygen, and produce energy.
The host proteins characterized in this study may potentially reflect how DV infection disturbs the function of the cellular proteome.
As a consequence of the microenvironmental changes, the altered ECM synthesis in the presence of inflammation, in turn, further disturbs the functions of the cells.
Such an "improper" neuronal transmission disturbs the function of extensors and flexors motoneurons by interneuronal connections bilaterally which finally change the muscles activity and their force during the long-lasting effort [ 34].
At cell level the heating cause damage by disturbing the functioning of proteins.
Especially at high HA amplification levels, the presence of strong feedback components in the sensor inputs may, therefore, seriously disturb the functioning of the BAF.
Depending on this table, for all interfering ions used, the selectivity coefficients are in the order of 10−3 or lower proving that they would not significantly disturb the functioning of the CLP selective electrode.
Due to the required low speed of the ride, a need to organize the measurements at night was decided so as not to disturb the functioning of regular tram transport.
These neuropsychological modifications induced by STN DBS suggest that this neurosurgery may disturb the functioning of associative and limbic circuits: neuroanatomical studies in animals have already demonstrated that the STN can be divided into sensorimotor (dorsolateral), limbic (medial) and cognitive-associative (ventromedial) areas (Parent and Hazrati, 1995; Joel and Weiner, 1997).
Most natural mutations in Vpr not only do not disturb the functions of the protein but also potentiate the protein for an increased functionality.
