Sentence examples for disturbed turnover from inspiring English sources

Overexpression of TMEM106B inhibits lysosomal function, thereby leading to disturbed turnover of PGRN [ 8].

CortactinS405 phosphorylation was mediated by ERK1/2 kinases and might trap activated FAK leading to a disturbed turnover of focal adhesions [ 82].

Our results indicate that DAOA gene variation affects dopamine turnover in healthy individuals, suggesting that disturbed dopamine turnover is a possible mechanism behind the observed associations between genetic variation in DAOA and behavioral phenotypes in humans.

In conclusion, we detected a disturbed spine turnover within the peri-plaque region that was caused by a loss of stable spines.

Bone loss is already seen in early AS and is due to disturbed bone turnover rather than immobility caused by syndesmophytes [ 6, 9, 15- 17].

These findings imply an important role for COX-2 in the disturbed proteoglycan turnover in OA, whereas COX-1 plays a more physiological role in the chondrocytes.

Thus, it is possible that a disturbed dopamine turnover, reflected by decreased HVA levels, may be a mechanism behind one or several of the cognitive, neurological and brain morphological phenotypes previously associated with the rs3918342 TT genotype.

Disturbed alveolar fibrin turnover is a cardinal feature of severe pneumonia.

Disturbed alveolar fibrin turnover during MV in healthy lungs seems solely the result of activation of coagulation.

The mechanisms that contribute to disturbed alveolar fibrin turnover are thought to be similar to those found in the intravascular spaces during severe systemic inflammation [ 9].

In pneumonia alveolar fibrin turnover is disturbed by activation of coagulation and inhibition of fibrinolysis.