Fast-wave sleep in rats is considered to be analogous to REM sleep in humans, which has been suggested to be especially disturbed in insomnia (Riemann et al., 2012).
Interestingly, our study also allows us to better understand how sleep is disturbed and leads to insomnia in LUTS/BPE patients.
Hence sleep quality seems to be more vulnerable (i.e. disturbed by anxiety or subjective insomnia) among migraineurs than healthy controls.
**Among 17 symptoms: stiffness, headaches, tiredness, tiredness on waking up, exhaustion, insomnia, disrupted or disturbed sleep, sensitive to cold or heat, sensitive to smells, sensitive to noise, sensitive to touch, problems remembering things, problems concentrating, nausea, diarrhoea, constipation and problems with urination.
Measures of HRV have also been found disturbed in sleep disorders such as sleep apnea and insomnia.
In this framework, insomnia is a condition not just of losing sleep but of being disturbed by sleeplessness.
The term sleeping sickness derives from the symptoms of this second phase, in which the circadian rhythm is disturbed, resulting in bouts of fatigue alternating with manic periods, progressing to daytime slumber and nighttime insomnia.
However, if sleep quality is not good, such as with sleep disorders like insomnia, restless legs syndrome or sleep apnea this synchronised relationship between sleep and appetite may be disturbed.
