Sentence examples for disturbed expressions from inspiring English sources

We describe the induction of embryonic senescence and laminopathies in zebrafish harboring disturbed expressions of the lamin A gene (LMNA).

Disturbed expression of splicing factors was reported in several types of cancers [11].

Apart from disturbed expression, several other factors may also contribute to improperties in functionality of splicing factors.

We suggest that changes in correlation between expression levels of splicing factors may potentially serve as markers of carcinogenesis in ccRCC and that splicing factors may possibly constitute therapeutic targets in patients with disturbed expression of specific splicing regulators.

It is notable that although most of the publications refer to tumor-specific increase of splicing factors expression, the percentage of samples in which the disturbed expression occurs is rarely shown.

In addition, to investigate the consequences of disturbed expression of splicing factors, we analyzed existence and expression of transcripts of five genes involved in tumorigenesis, that are known to be alternatively spliced and partially regulated by the analyzed splicing factors.

Moreover, we [21] could previously show that NPS, via NPSRs in the EPN, alters the activity of both projection neurons and interneurons in the BLA, leading to a disturbed expression of contextual fear memory.

Disturbed expression of some neurotransmitters and their receptors has been shown in the central nervous system of SIDS victims but no biological abnormality of the peripheral vago-cardiac system has been demonstrated to date.

We conclude that disturbed expression of splicing factors in ccRCC may possibly lead to impaired alternative splicing of genes regulating tumor growth and therefore contributing to the process of carcinogenesis.

Especially in the hypothalamus, a disturbed expression of Se-dependent Dio might contribute to the aetiology of the syndrome [13], but the exact molecular alterations have not been fully clarified [14].

We conclude that disturbed expression of splicing factors in ccRCC may possibly lead to impaired alternative splicing of genes regulating tumor growth and this way contribute to the process of carcinogenesis.