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I check my smile and will myself into a more appropriately disturbed expression.
A different approach to further focusing on specific potential phenotypes was applied by Zarbalis et al. [5], who used disturbed expression of a Dlx5/6-LacZ transgene as screening criterion.
Disturbed expression of splicing factors was reported in several types of cancers [11].
Apart from disturbed expression, several other factors may also contribute to improperties in functionality of splicing factors.
Moreover, we [21] could previously show that NPS, via NPSRs in the EPN, alters the activity of both projection neurons and interneurons in the BLA, leading to a disturbed expression of contextual fear memory.
Disturbed expression of some neurotransmitters and their receptors has been shown in the central nervous system of SIDS victims but no biological abnormality of the peripheral vago-cardiac system has been demonstrated to date.
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We describe the induction of embryonic senescence and laminopathies in zebrafish harboring disturbed expressions of the lamin A gene (LMNA).
The strong, constitutive promoters of retrotransposons can disturb expression of nearby genes, either directly or via the spread of repressive epigenetic marks associated with retrotransposons.
Cytokeratin expression in the tumors was profoundly disturbed, including expression of CK5 and CK8 (characteristic of basal and luminal cells, respectively) throughout the epithelial component of the tumors, CK6 (potentially a stem cell marker), CK10 (a marker of interfollicular epidermal differentiation), and mIRSa2 and mIRSa3.1 (markers of the inner root sheath of hair follicles).
Therefore, whereas the global shape of the embryos kept highly disturbed, the expression of GsbN in NBs 6-4 and 7-3 wasufficientntoto rescue both axon growth and crossing of the midline.
The disturbed Cxs expression in prostate cancer may be related to the hormones and growth factors that are secreted by the cancer and its microenvironment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com