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(B and C ) Cell cycle distributions for control and SRSF1-depleted cells were monitored by flow cytometry in asynchronous cells (B ) and in cell cultures synchronized with a double thymidine block following release for 0 10 hr (C ).
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Genotype distributions for controls were consistent with HWE, and the average call rate for the analysed SNPs was 97.5% (range: 95.6% to 98.7%).
The dominant circulating influenza type and subtype varied over the two seasons: 23% of cases in 2007 were A/H1N1, 60% were A/H3N2 and the remainder were type B; the respective proportions in 2008 were 4%, 36%and57%7% (table 3). a Age unknown for one case Age group, sex and month of swab collection distributions for controls and cases (including type and subtype strata) are shown in table 3.
To create a normal distribution for control subjects, we identified 10 subjects with no comorbidities or gait dysfunction.
The age of mothers at the birth of the index child shows a close approximation to a normal distribution for control mothers.
The distribution for control cells displayed a leftward shift from time 0 4 h after STS treatment compared with that of +IF1 cells, showing that more control than +IF1 cells had undergone Cyt c redistribution.
Frequency distributions for both control and SMA slices could be fit with three Gaussian peaks, but in control slices serotonin caused a much larger change in the frequency distribution, dramatically shifting activity from the low frequency range into the middle and high frequency peaks (Fig. 3).
We also assessed deviation from HWE in controls for all the included studies, and the results demonstrated that most genotype distributions for the control group were well goodness-of-fit except for five studies.
Other state time distributions for the control target are shown in the Supporting Information, Figure S4.
We provide simple diagnostic plots which indicate that the relative center and scales of the underlying distributions for the control and spike-in expression values vary as a function of signal intensity.
Indeed, the distribution plot for control cells at 4 h was fitted well by the sum of two Gaussian distributions representing the two sub-populations of cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com