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Chiu et al. (2006) concludes that pending the evaluation of a number of additional structural hypotheses, such as enterohepatic recirculation, plasma binding, and flow- or diffusion-limited treatment of tissue distribution, rigorous application of PBPK modeling to risk assessment appears feasible at least for TCE and its major oxidative metabolites, trichloroacetic acid (TCA) and trichloroethanol.
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The improved EL performance was attributed to uniform distribution and rigorous confinement of carriers and excitons.
The achievement of high EL performance with type-I MQW structure WOLEDs would be attributed to the uniform distribution and rigorous confinement of carriers and excitons within EMLs.
The new procedure will allow physicians and scientists to design and optimize invasive drug delivery techniques systematically based on in-vivo drug distribution data and rigorous first principles models.
This involves a two step procedure – first the determination of the in-plane stress distribution using a rigorous superposition approach and then the analysis for stability using Galerkin's method.
We illustrated the loci of the portion of current distribution by a rigorous cutoff value of the z-transform of the difference vector between conditions (but also inspected results after a non-rigorous threshold), for the attention-related frequencies.
In this case, we were able to develop rigorous distribution hypotheses for 15 species of mammals and insects that interact in the potential transmission of Chagas disease in Mexico.
Proving that PPI networks follow a power law degree distribution requires more rigorous statistical data analysis than that available today [ 44]; however, it is clear that the connectivity of the PPI networks is centralized around a small number of hub nodes.
To calculate the SCBD and molecular weight distribution (MWD) simultaneously, a rigorous process model (i.e., kinetic model, thermodynamic model, reactor model) combined with a specific calculation method is established.
If, for practical reasons, models with homogeneous properties within each layer are used, we recommend setting nonzero Kds in the vitric tuffs to mimic the more rigorous continuous distribution simulations.
In some other cases, statistical tests have been carried out in a way that is somewhat questionable in the sense that the determination of the critical values and the P-values is not adequately justified due to lack of a rigorous statistical distribution theory of the deviance measures used for such tests.
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CEO of Professional Science Editing for Scientists @ prosciediting.com