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As both the overall conservation of the protein and the location of these sites may have a significant impact on conservation scores, we calculated the RCRs for 41 residues around the site under study (±20 residues) to build the reference distribution of conservation for the flanking regions.
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Involving the local community in biodiversity assessment offers a simple short cut to clarify the presence and distribution of conservation target species in any area where limited resources for conservation are a constraint.
This is in agreement with the observed distribution of conservation scores in which an under-representation of recessive disease genes is observed for very high conservation scores.
We also found that the distribution of conservation scores of conditional exons is bimodal.
It clearly shows that the distribution of conservation scores of conditional exons is bimodal.
(c) This panel shows the distribution of PhastCons scores, reflecting the extent of conservation for known, partially novel (novelty score < 70%) and completely novel (novelty score ≥ 70%) transcripts identified across developmental stages in lens.
Modern tools for cost-effective conservation reserve site planning require the planner to have information about spatial distributions of conservation costs and benefits.
We calculated the distribution of the conservation ratio for each motif mode based on the logarithmic binning.
We can fit the distribution of the conservation ratio for all motif modes on a logarithmic scale by employing a quadratic function if the value of the first bin (0~2) is not taken into account (R square = 0.97, p < 0.001).
These global-scale prioritisations affect the distribution of funds for conservation interventions.
The plot of promoter conservation levels against protein conservation is shown in Figure 4. Apparently, the protein conservation is drastically different between cytoplasmic and mitochondrial ribosomal proteins, whereas the distribution of promoter conservation is quite similar.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com