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If the distribution in the bladder wall after administration of BoNT-A could be monitored, the differences in clinical effect among patients might be better understood.
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Microscopic evaluation of the spatial drug distribution in bladder, prostate and tongue indicates heterogeneous drug distribution with large and erratic concentration gradient.
De Jongh et al. found differences in the number and distribution of cGMP+ ICs in the bladders of guinea pigs with surgically induced bladder outflow obstruction [ 17].
It had led to bladder stones and blood in the bladder.
"It doesn't brown in the bladder," the waiter says.
Simonyi: The fluids are behaving differently in the bladder.
For example, bladder contractions can be weaker, which means some urine tends to pool in the bladder.
Subsequently, a suprapubic catheter is placed in the bladder.
Colovesical fistula present with free air in the bladder with thickening of the adjacent bladder wall [30].
Although a dimple in the bladder was clear, an IVP is not the first choice to diagnose bladder disease.
Other factors are the intrinsic bladder compliance and the amount of instilled fluid in the bladder [1, 4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com