The degree of TIL distribution changes exerted by chemotherapy was related to pathological response: a higher (over the median) chemotherapy-induced decrease of the total infiltration by T cells (CD3) was significantly related to pCR even after adjusting for tumor subtype in the multivariate analysis (P = 0.001; OR = 17.84, 95% CI 3.02 to 105.27).
The paper aims at evaluating and improving the accuracy of bird impact numerical analyses performed with finite element explicit codes, focusing on the modelling of the spatial and temporal pressure distributions exerted on the target by the impacting body.
The discrete element method (DEM) provides a means of studying the handling and silo discharge behaviour of granular solids as well as the distribution of the pressures exerted by such materials in silos.
Beside the five major histones, several variants with unique distribution patterns and functions not exerted by the "classic" histones have been described [ 36, 37].
It also considered a number of landscape and cultural characteristics of the region taking into account the influence exerted by the geographical distribution of these resources.
Finally, the distribution of the normal and shear stresses exerted by the fluid on the surfaces of two simultaneously moving porous spheres is calculated for various permeability values.
Closed-form load distribution solutions for calculation of the loads exerted by the rolling elements on the outer raceway in cylindrical and spherical roller bearings under radial loading are proposed.
Even though stress distribution in the developing scapula has not been studied, forces exerted by the mice with development (1 week to 4 weeks) in forelimbs have been studied using a dynamometer [27].
Data suggest that the cause for observed discrepancies is the strong influence exerted by grain boundaries and grain orientation on the distribution of stress and strain within the matrix.
