Sentence examples for distribution brain from inspiring English sources

Since brain exposure of any molecule is a function of peripheral distribution, brain penetration, and metabolism, this fact has to be taken into consideration while assessing the results.

Similarly, alteration in renal elimination resulted in increased brain distribution (brain-to-plasma ratio: 10.98 vs. 6.88).

unbound drug concentrations, as it is the unbound drug concentration that drives transport processes (BBB transport, intra-brain distribution, unbound brain concentrations) and target interactions that lead to drug effects (69, 70).

The effect of these transporters on cefadroxil distribution in brain is unknown, especially in the extracellular and intracellular fluids within brain.

Drug distribution between brain cells and extracellular space does not only occur by simple diffusion: active transport may also occur at brain cell membranes [ 68, 84].

Distribution of brain HIV load in AIDS.

Yamamoto, S. et al. Development of a high resolution beta camera for a direct distribution on brain surface.

Spending time in space causes dramatic shifts in body fluid, but potential changes in the distribution of brain fluid are a new concern.

In addition to quantitative analysis of AV-45 autoradiograms, we performed thioflavin-S fluorescent staining to confirm the plaque distribution in brain sections.

This was primarily based upon the observation of discrete distribution of brain infarcts after embolic occlusion of particular vessels.

Finally, liposomal encapsulation of doxorubicin reduced its tissue affinity and substantially increased its distribution within brain tumor tissue.