In live OK cells, mEOS2-fused NHERF1 and NHERF2 were co-localized with the apical surface marker WGA and primarily distributed to microvillar clusters in similar morphology as demonstrated previously by electron microscopy [ 36].
For example, P450s included in clan FF59 were distributed to four P450 clusters (Clusters 4.1, 8.1, 31.1 and 73.1).
Determined samples (630) were proportionally distributed to each cluster (probability proportional to size (PPS based on number of eligible children in each cluster after enumeration of selected clusters.
Since a central random number generator whose output is distributed to each cluster incurs a large communication overhead, we propose to use identical pseudo-number generators in all clusters and initialize those with the same seed, thereby ensuring that all clusters perform the same (re)sampling (cf. with [24] and [26]).
This means that the computation can be efficiently parallelized and distributed to a cluster of machines.
Thirdly, due to the frequent update of the unigene database, some unigene clusters were retrieved, the ESTs in the clusters might be retracted or distributed to other new clusters (http://www.ncbi.nlm.nih.gov/UniGene/help.cgi item=FAQ), and the microarray data couldn't catch up with the update of unigenes, so there will be lots of unigenes have no corresponding probesets.
It employs the MapReduce paradigm to divide the computation tasks into parts that can be distributed to a commodity cluster and therefore, provides horizontal scalability [2] [9].
These problems revealed from the interim analysis led to the following conclusions which were documented in a note to file: 1) 160 patients will be required, distributed to four patients per cluster with twenty clusters per treatment arm.
WT NHERF2 and NHERF2 S303A were both primarily distributed to the apical microvillar clusters, whereas NHERF2 S303D was localized in both the microvilli and the cytosol.
The CFEM domain is also common in Pezizomycotina and Basidiomycota, but the corresponding proteins distribute to other clusters, none of which shows full coverage of a specific phylogenetic lineage as cluster 320 does.
