Capturing cardiomyocytes in mitosis, revealed AK1 distributed in the nucleus where it associated with centrosomes and the mitotic spindle in metaphase (Fig. 2E).
As the cell prepares to enter mitosis, xMELK protein is diffusely distributed in the cytoplasm at interphase, however, during anaphase and telophase, xMELK is associated with the cleavage furrow of dividing cells.
Both the mitotic numbers and Ki67 percentages were differently distributed in the pNR and pCR + pPR categories (mean values: 8.5 vs 11.3 for mitosis and 27.9 vs 38.4 % for Ki67; SDs: 10.2 vs 12.1 for mitosis and 14.9 vs 25.7%% for Ki67) (p = 0.046 and 0.001, respectively) (Fig. 1).
However, as these cells are characterized by increased nuclear granularity as well as by variable densitometry (because of the presence of apoptotic bodies), they show a greater heterogeneity than cells arrested in mitosis, thereby distributing all over the four quadrants of the diagram (which limit their influence on total records; Figure 3b).
The new polyploid macronuclei are distributed passively in the first of these divisions; in subsequent fission, the macronuclei duplicate themselves through a form of mitosis.
In mitosis, mitochondria, which are usually present in the cytoplasm as well as in the chloroplasts of algae and plants, are smoothly distributed with the chromosomes to offspring cells.
The cells in mitosis were detected through immunochemistry using an anti-H3-P antibody.
Minocherhomji, S. et al. Replication stress activates DNA repair synthesis in mitosis.
Aurora B is a chromosomal-passenger protein with multiple functions in mitosis.
Sharp, D. J., Rogers, G. C. & Scholey, J. M. Microtubule motors in mitosis.
