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At 20 weeks of follow up c Color fundus picture shows healed, pigmented, and scarred lesion infero-temporal to fovea and d OCT scan over the lesion shows reduced retinal thickness, distorted architecture of retinal layers temporal to the fovea, reduced amount of subretinal fluid, and relative restoration of the foveal contour.
You blink once, then twice, at the dizzying layers of distorted architecture, realizing this meta-photograph is in fact two-dimensional.
The distorted architecture, along with loss of normal cellularity, leads to a loss of function of the underlying organ.
One explanation as to why bioimpedance increases in cancer tissue is the distorted architecture of the gland, which prevents flow of current.
On the basis of mammograms, the women who were reported to have a mass, distorted architecture, density or calcification in the breast tissue were excluded from the study (from the control group).
On the other hand, excess production and accumulation of ECM structural proteins, or fibrosis, results in enhanced stiffness of the myocardium and impedes ventricular contraction and relaxation, leading to distorted architecture and function of the heart.
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Moreover, Group II rats showed distorted hepatic architecture and fat accumulation in hepatocytes.
Fibrosis is a hallmark of many myocardial pathologies and contributes to distorted organ architecture and function.
There were bundles of collagen surrounding the lobules that resulted in large fibrous septa and distorted tissue architecture.
In addition, increase in Kupffer cells (Fig. 1e), eosinophilic material, infiltration of inflammatory cells, and distorted hepatic architecture was evident (Fig. 1f).
f Photomicrograph of liver section from treated rat of high dose showing eosinophilic material (black arrow), infiltration of inflammatory cells (black arrow with two heads), and distorted hepatic architecture (H&E ×400).
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