Exact(1)
However, to our surprise, knockdown of miR-148b resulted in no remarkable changes in the expression of EMT-related genes, such as BMI 1, SNAI 1, TWIST 1, CDH 1 and CDH 2. Although it was reported that BMI 1 was up-regulated in SP cells in HCC [ 27], we proposed that miR-148b might regulate the maintenance of SP cells in HCC through the distinguished pathway from BMI 1.
Similar(59)
This preference might manifest as spatially distinguished pathways because recent EM studies in yeast have suggested that mRNPs traffic mainly through the center of the NPC's channel whereas karyopherins pass through the channel's periphery (Fiserova et al. 2010).
The slow-growth phenotype of the triple mutant strain made it difficult to distinguish pathway specific effects from general sickness in this strain.
In light of these discrepancies in the outcome of cellular survival from these studies further global proteomic analyses hope to distinguish pathways and proteins essential for mediating cell survival by SirT3.
Second, what distinguishes pathway-level perturbations by chemicals that affect one species differently from the other?
Similarly, GoSynthetic distinguishes pathways (full well known pathways such as glycolysis, TCA and pentose biosynthetic process / pentose phosphate pathway) from transformations (no full pathways).
-wrap> To distinguish pathways differentially enriched in either the EPI or TE we performed a comparative analysis of signalling pathways operating in these two lineages.
For both dichotomous comparison of low- versus high-BPA sample groups and the continuous linear models, LRpath was performed using the directional option with default settings, to distinguish pathways enriched with hyper- versus hypo-methylated sites.
For example, some cellular processes like inflammation, epidermal migration, and cell proliferation are common to all injury types, so it is necessary to devise experimental strategies that can distinguish pathways specific to general injury processes from those required for appendage regeneration.
This hints there may be a distinguishing pathway whereby NRP-1 mediates EC survival through its intracellular domain and is independent of VEGFR-2 signaling.
The literature does not distinguish which pathway is affected by this phosphorylation (clathrin dependent versus independent), and in this sense the paper contributes a new view.
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