Because it is impossible to distinguish at the time of diagnosis between an overdiagnosed cancer and one that will become clinically meaningful, measurement of overdiagnosis is not straightforward.
Nonsevere Clostridium difficile infection (CDI) and severe CDI, which carries a higher risk than nonsevere CDI for treatment failure and CDI recurrence, are difficult to distinguish at the time of diagnosis.
He had on jeans, a canary yellow shirt, a charcoal blazer, and an ascot; he looked "mod" and distinguished at the same time.
These two possibilities cannot be distinguished at the present time because mucin granules cannot be clearly identified by electron microscopy in naive WT mice [ 10].
Thus, interpretation of the phylogenomic analysis of viral genes, to a large extent, hinges on the choice between the two orthogonal scenarios for the origin of eukaryotes that cannot be definitively distinguished at this time.
The urinary system could be distinguished at the 60-min time point, with the ureter and urinary bladder defined clearly.
Although more categories (e.g., xylem vessels and parenchyma cells separately) could be reliably distinguished at individual time points using other classifiers, we restricted our analyses to these five for the sake of a coherent temporal description of secondary growth progression.
Since clinical signs and symptoms of acute renal damage are not specific [ 3, 6, 7] it is difficult to promptly distinguish AKI at the time of ED presentation.
The challenge of progressive alignment is that insertions cannot be distinguished from deletions at the time of aligning a pair of sequences but failing to account for their different properties is likely to cause alignment error (Löytynoja and Goldman, 2008).
According to one view, material objects persist by having temporal parts or stages, which exist at different times and are to be distinguished by the times at which they exist – this is known as the view that material objects perdure.
