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The analysis of liver samples identified 123, 115, and 67 proteins that distinguished (adjusted p values ≤ 0.05) young control mice from young ob/ob, db/db, and HFD-fed mice, respectively, and also 74, 79, and 41 proteins that distinguished old control mice from old ob/ob, db/db, and HFD-fed mice, respectively (Table 1).
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Figure 2 shows, for the whole period, the debt decomposition into primary deficit (PD), snow-ball (SB) and stock-flow adjustments (SFA) as presented in Eq. 2.2, but distinguishing between cyclically adjusted and cyclical components of primary deficit.
We can distinguish between global models, adjusted with experimental tests, and local models, based on the constitutive equations for materials.
Brightness and contrast of the bilayer region was adjusted to distinguish mono- and bilayer regions.
Photomerged images were imported into ImageJ and threshold levels were adjusted to distinguish tumour from background.
Finally, for the Oil red O analysis, the colour density threshold was adjusted to distinguish all the fat droplets on a single fibre.
Detection thresholds for the size, circularity and differences in contrast of the nuclei can be adjusted to distinguish cancer cells from other cell types such as fibroblasts or lymphocytes.
This gave us an opportunity to distinguish between and adjust for full and partial breastfeeding or formula feeding in the analysis which has earlier been shown to be related to the time for introduction of solid food [ 4].
3,322 probesets (fold change >2 or < -2; p adjusted value < 0.01) distinguished AM from BMDM and 3,058 distinguished AM from MDM.
Only 144 probesets (fold change >2 or < -2; p adjusted value < 0.01) distinguished the cultivated macrophages; 69 elevated in MDM and 75 in BMDM, essentially confirming the similarity of the populations indicated by PCA analysis.
Main outcome measures Primary outcomes were parasitological cure rates after 28 days of follow-up unadjusted and adjusted by genotyping to distinguish recrudescence from new infections.
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