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The evidence suggests that distinguishable target proteins are involved, resulting in the different outcomes toward pseudopodia suppression.
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Following hybridization of spectrally distinguishable labeled targets to the arrayed probes on a microarray, the surface of the slide is generally interrogated using one or more lasers, each tuned to excite a particular fluorescent label.
Therefore, some pure noise pixels are evidently distinguishable from the target support in some range bins, with which the noise variance can be estimated straightforwardly.
spp. The latter showed melting curves very similar to C. officinalis but distinguishable from our target species by the trnK primers (Fig. 1D).
As a positive control [ 74- 76], we included DNA from a fresh larval sample of the distantly related Hyles livornica (MTD-# 7528; ~30 ng DNA per reaction), which is clearly distinguishable from the target sequences in every fragment (Additional file 2: Table S2).
To determine the "optimal" σ and make the noise and targets distinguishable, a different perspective should be taken.
The R1677X mutation was detected by a melting curve at 60.0°C and the R1677P mutation at 56.3°C, both distinguishable from the targeted mutation.
This pairwise appearance model focuses on distinguishable features from two targets without considering other targets or backgrounds, therefore it is more effective for differentiating specific close-by tracklets pairs.
Once a probe is selected, it is included within the probe set and all targets that are covered by this probe and are distinguishable from all other targets are removed from consideration when assessing a future candidate probe's coverage of targets.
Therefore, it seems possible to find some candidate miRNAs and conserved target sites distinguishable between HR-HPVs and LR-HPVs.
One additional validity consideration relates to the presence of bias in the items across distinguishable subgroups within the target population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com