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Given the observed impaired recycling of β1-integrin, its accumulation in enlarged endosomes in CEDNIK cells (Figure 6) and the distinguishable expression pattern of FAK, PAX and their phosphorylated forms in peripheral adhesions (Figure 7), we examined the ability of CEDNIK cells to migrate and spread using wound healing and cell spreading assays.
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Although the principal component analysis revealed that the two groups of cells show distinguishable expression patterns, we were not able to link these differences to one or multiple particular HERV families.
This made us wonder if these two classes of hli genes had distinguishable expression patterns under these optimal growth conditions.
Hierarchical clustering was performed to highlight the expression pattern of the distinguishable mRNAs and lncRNAs between the two samples.
Expression pattern of OsMYB61.
Fig. 4 Expression pattern of OsSND2.
The expression pattern of HO-1 resembled the pattern of CSE expression.
Expression pattern of pPLAIIIδ.
Expression pattern of miR156.
All cell types have their distinct expression pattern and they are clearly distinguishable from each other.
Armstrong et al discovered that MLL leukaemias have a distinct expression pattern and can be considered as a separate disease distinguishable from ALL and AML.
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