Accordingly, ASA does not have the capacity to readily distinguish a substantially buried residue that is nevertheless close to the surface from a residue that is truly completely deep in the hydrophobic core; for both cases the ASA value would be zero or near zero.
Pockets of high velocity produced by moving legs could be distinguished and substantially extended the region of flow influenced by the spider (Figure 2).
The first corresponded with the approximate top ranked 300 500 genes, which are clearly distinguished by substantially greater modification.
Several smaller and less stable molecular subsets (such as normal-like, HER-2-positive and claudin-low) have also been proposed but are less consistently seen and are distinguished by substantially smaller molecular differences [ 4, 5].
Previous attempts failed to provide clear clinical recommendations or to distinguish subgroups that substantially benefit from a certain treatment strategy.
Results compare favorably against the original reanalyses as well as the leading climate forcing datasets (Princeton, WFD, WFD-EI, and GRASP), and AgMERRA distinguishes itself with substantially improved representation of daily precipitation distributions and extreme events owing to its use of the MERRA-Land dataset.
However, it has to be kept in mind that on grounds of the still scarce information at the present time, this is a very crude approximation and, especially important, that for most XME, these data do not yet distinguish between isoenzymes, which may substantially vary in their substrate specificities.
That led to a guilty finding under New York's insanity law, which holds the mentally ill responsible for crimes unless they are unable to distinguish right from wrong and are substantially unable to appreciate the consequences of their acts.
Forcing PMD into the BANN-trained classifier did not substantially alter our ability to distinguish between BRCA1/2 mutation carriers and non-carriers (P = 0.06).
However, currently available primer design programs do not distinguish between splice variants and also differ substantially in overall quality, functionality or throughput mode.
